Infasurf is a pure surfactant that contains only active surfactant unlike our competitors, which contain lung tissue contaminants. Infasurf delivers the highest level of Surfactant Protein B (SP-B), the closest to natural lung surfactant.
Surfactant Protein-B plays two critical roles: it is the essential activator of the surfactant film and SP-B protects the surfactant film from disruptive inflammatory mediators and this is a concentration dependent response (stoichiometric). The more SP-B you have, the more the film is protected. The less SP-B you have, the less the film is protected.
Competitive surfactants also create a film but only Infasurfis sufficiently rugged to withstand inhibitory proteins like fibrinogen, hemoglobin and albumin. This composition is the reason that Infasurf has optimal immediate and sustained surfactant effects.
